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Flipping the Switch on Sleep-Related Breathing Disorders
Shallow breathing while you sleep shouldn’t shadow your entire day.
If you live with obesity hypoventilation syndrome or COPD-related hypoventilation, consider exploring your options through research.
Learn more about the NOCTAVA Study today.
You may be able to participate in the NOCTAVA Study if you:
Are 21 to 75 years of age
Have been diagnosed with obesity hypoventilation syndrome or COPD-related hypoventilation
Are not currently using or are unwilling to use positive airway pressure (PAP) therapy and supplemental oxygen
If you are interested in participating,
the study doctor or staff will review additional study criteria with you.
About the NOCTAVA Study
The NOCTAVA Study is a clinical research study for adults with obesity hypoventilation syndrome (OHS) or COPD-related hypoventilation. It is looking at whether an investigational medication may help with breathing problems.
During the study, participants will be placed by chance into 1 of 3 groups. Two groups will receive different doses of the investigational medication, and 1 group will receive a placebo, which looks like the investigational medication but has no active ingredients. Participants will take the tablets by mouth.
If you qualify and choose to participate, the study will last about 9 weeks and include up to 6 visits: 5 at the study center and 1 by phone. At study center visits, the study team will check your vital signs (such as blood pressure and heart rate), perform physical exams and heart tests (electrocardiograms, or ECGs), and collect blood and urine samples. Two study center visits will require an overnight stay, during which the study team will assess your breathing and sleep. At home, you will complete a daily electronic diary, wear an activity-monitoring device from screening through Day 35, and use a separate small sleep-monitoring device for 2 nights during the week before each study center visit.
